High school student^^, Undergraduate student^, Masters student+, PhD student*, Postdoctoral researcher#, Corresponding author

2024

75. Oral Delivery of Nanomedicine for Genetic Kidney Disease. Y. Huang, J. Wang, V. Mancino, J. Pham, Colette O’Grady, H. Li, K. Jiang, D. Chin, C. Poon, P. Y. Ho, G. Gyarmati, J. Peti-Peterdi, K. Hallows, E.J. Chung, PNAS Nexus. [in press]

74. Natural Killer Cell-Derived Extracellular Vesicles as Potential Anti-Viral Nanomaterials. S. Lim, N. Ho, S. Chen, E.J. Chung. Advanced Healthcare Materials. [link]

73. Investigation of Basolateral-targeting Micelles for Drug Delivery Applications in Polycystic Kidney Disease. Y. Huang, A. Osouli, J. Pham, V. Mancino, C. O’Grady, T. Khan, B. Chaudhuri, N. Pastor-Soler, K. Hallows, E.J. Chung. Biomacromolecules. [link]

72. MRI Detection of Lymph Node Metastasis Through Molecular Targeting of CCR2 and Monocyte Hitchhiking. N. Trac*, Z. Chen^, H. Oh^, L. Jones^, Y. Huang*, J. Giblin*, M. Gross, N. Sta Maria, J. Russell, E.J. Chung. ACS Nano. [link]

71. Nanoparticle-based Therapeutic Strategies for Mitochondrial Dysfunction in Cardiovascular Disease. I. Suzuki#, H. Xing#, J. Giblin*, A. Ashraf*,  E.J. Chung. JBMR-A. [link]

2023

70. Nanoparticles-based Technologies for Cholera Detection and Therapy. N. Ho^, K. Tang^, I. Livitz^, A. Morrell^, B. Noor^, K. Tseng^, E.J. Chung. SLAS Technology. [link]

69. Targeting the ADPKD Methylome Using Nanoparticle-mediated Combination Therapy. A. Trinh, Y. Huang*, H. Shao, A. Ram+, J. Morival, J. Wang*, E.J. Chung, T. Downing. APL Bioengineering. [link] [Scilight feature]

68. Long-term, In Vivo Therapeutic Effects of a Single Dose of miR-145 Micelles for Atherosclerosis. D. Chin*, N. Patel*, W. Lee^, K. Sonali^, J. Cook^, E.J. Chung. Bioactive Materials. [link]

67. Spotlight on Genetic Kidney Diseases: A Call for Drug Delivery and Nanomedicine Solutions. N. Trac*, A. Ashraf*, J. Giblin, S. Prakash, S. Mitragotri, E.J. Chung. ACS Nano. [link]

66. In Vitro Delivery of mTOR inhibitors by Kidney-Targeted Micelles for Autosomal Dominant Polycystic Kidney Disease. A. Cox#, M. Tung^, H. Li, K. Hallows, E.J. Chung. SLAS. [link]

65. Extracellular Vesicles as Regulators of the Extracellular Matrix. N. Patel*, A. Ashraf*, E.J. Chung. Bioengineering, 10(2): 136. [link]

2022

64. Combining Metformin and Drug-Loaded Kidney-Targeting Micelles for Polycystic Kidney Disease. K. Jiang^, Y. Huang*, E.J. Chung. CMBE. [link]

63. CD70-Targeted Micelles Enhance HIF2a siRNA Delivery and Inhibit Oncogenic Functions in Patient-Derived Clear Cell Renal Carcinoma Cells. N. Trac*, H.S. Oh^, L. Jones^, R. Caliliw, S. Ohtake, B. Shuch, E.J. Chung. Molecules, 27(23): 8457. [link]

62. Oral Delivery of Kidney Targeting Nanotherapeutics for Polycystic Kidney Disease. Y. Huang, J. Wang, D. Chin, V. Mancino, J. Pham, H. Li, K. Jiang, A. Ram, C. Poon, P. Y. Ho, G. Gyarmati, J. Peti-Peterdi, K. Hallows, E.J. Chung, bioRxiv: Preprint. [link]

61. Beneficial Effects of Bempedoic Acid Treatment in Polycystic Kidney Disease Cells and Mice. K. Hallows, H. Li, B. Saitta, S. Sepehr, P. Huang, J. Pham, J. Wang*, V. Mancino, E.J. Chung, S. Pinkosky, N. Pastor-Soler. Frontiers in Molecular Biosciences. [link]

60. Therapeutic Response of miR-145 Micelles on Patient-Derived Vascular Smooth Muscle Cells. N. Patel*, D. Chin*, G. Magee, E.J. Chung. Frontiers in Digital Health. [link]

59. Immunization Using ApoB-100 Peptide-Linked Nanoparticles Reduces Atherosclerosis. K.Y. Chu, X. Zhao, P. Dimayuga, W. Lio, B. Cercek, N. Trac*, E.J. Chung, P. Shah. JCI Insight. [link]

2021

58. Targeted Polyelectrolyte Complex Micelles Treat Vascular Complications In Vivo. Z. Zhou, C. Yeh, M. Mellas, M. Oh, J. Zhu, R. Huang, D. Harrison, T. Shentu, D. Wu, M. Lueckheide, L. Carver. E.J. Chung, L. Leon, K. Yang, M. Tirrell, Y. Fang. PNAS, 118(50): e2114842118. [link]

57. Clinical Progress of Nanomedicine-based RNA Therapies. S. Lim*, A. Cox#, M. Tung^, E.J. Chung, Bioactive Materials. [link]

56. Exosomes in Atherosclerosis, A Double Edged Sword: Their Role in Disease Pathogenesis and Their Role as Novel Therapeutics. N. Patel*, D. Chin*, E.J. Chung, The AAPS Journal: In Press. [link]

55. Strategies To Deliver RNA by Nanoparticles for Therapeutic Potential. A. Cox#, S.A. Lim*, E.J. Chung, Molecular Aspects of Medicine: In Press. [link]

54. Improving Kidney Targeting: The Influence of Nanoparticle Physiochemical Properties on Kidney Interactions. Y. Huang*, J. Wang*, K. Jiang^, E.J. Chung, J of Controlled Release, 334 (10): 127-137). [link]

53. miR-145 Micelles Mitigate Atherosclerosis by Modulating Vascular Smooth Muscle Cell Phenotype. D. Chin*, C. Poon#, J. Wang*, J. Joo^, V. Ong^, Z. Jiang^, K. Cheng^, A. Plotkin, G. Magee, E.J. Chung, Biomaterials, 273: 120810. [link]

52. Overcoming Physiological Barriers by Nanoparticles for Intravenous Drug Delivery to the Lymph Nodes. N. Trac* and E.J. Chung, Experimental Biology and Medicine: In Press. [link]

51. Oral Delivery of Metformin by Chitosan Nanoparticles for Polycystic Kidney Disease. J. Wang*, D. Chin*, C. Poon#, V. Mancino, J. Pham, H. Li, P. Ho, K. Hallows, E.J. Chung, J Controlled Release, 329(10): 1198-1209. [link]

50. CCR2-targeted Micelles for Anti-cancer Peptide Delivery and Immune Stimulation. N. Trac*, L. Chen, A. Zhang, C. Liao, C. Poon#,  Y. Ando, J. Joo^, C. Garri, K. Shen, K. Kani, M. Gross, E.J. Chung, J Controlled Release, 329(10): 614-623. [link]

2020

49. Targeting and Therapeutic Peptide-based Strategies for Polycystic Kidney Disease. J. Wang*, N. Tripathy#, E.J. Chung, Advanced Drug Delivery Reviews, 161-162: 176-189. [link]

48. The Effect of Size, Charge, and Peptide Ligand Length on Kidney Targeting by Small, Organic Nanoparticles. Y. Huang*, K. Jiang^, X. Zhang^, E.J. Chung, Bioengineering and Translational Medicine, 5(3): e10173. Featured in the Futures issue. [link]

47. Transdermal Delivery of Kidney-Targeting Nanoparticles Using Dissolvable Microneedles. N. Tripathy#, J. Wang*, M. Tung^, C. Conway^, E.J. Chung, Cellular and Molecular Bioengineering, 13(5): 475-486.  Featured in the Young Innovator issue. [link]

46. Collagenase-Cleavable Peptide Amphiphile Micelles as a Novel Theranostic Strategy in Atherosclerosis. D. Chin*, C. Poon#, N. Trac*, J. Wang*, J. Cook^, J. Joo^, Z. Jiang^, M. Sulit Sta Maria, R. Jacobs, E.J. Chung, Advanced Therapeutics, 3(3): 1900196. [link]

45. Peptide-Based Targeting of Immunosuppressive Cells in Cancer. N. Trac* and E.J. Chung, Bioactive Materials, 5(1): 92-101. [link]

2019

44. Hydroxyapatite-Binding Micelles for the Detection of Vascular Calcification in Atherosclerosis. D. Chin*, J. Wang*, M. Mel de Fontenay^, A. Plotkin, G. Magee, E.J. Chung, J of Materials Chemistry B, 7: 6449-57. [link] Featured in the Emerging Investigators issue.

43. Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions, and Clinical Applications, Elsevier (book). E.J. Chung, L. Leon, C. Rinaldi (co-Editors)

42. A Brief History of Nanotechnology and Introduction to Nanoparticles for Biomedical Applications, Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions, and Clinical Applications, Elsevier (book chapter). L. Leon, E.J. Chung, C. Rinaldi.

41. Chapter 13: Hydrophobically-Assembled Nanoparticles, Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions, and Clinical Applications, Elsevier (book chapter). J. Wang*, M. Mellas, M. Tirrell, E.J. Chung. 

40. Nanoparticle Strategies for Biomedical Applications: Reviews from the University of Southern California Viterbi School of Engineering. E.J. Chung, SLAS Technology, 24(2): 135-136. Featured in the USC Students Nanomedicine special issue. [link]

39. Nanomedicine for Cystic Fibrosis. V. Ong^, L. Cao, K. Lee^, V. Mei^, E.J. Chung, SLAS Technology, 24(2): 169-180. Featured in the USC Students Nanomedicine special issue. [link]

38. siRNA-Conjugated Nanoparticles to Treat Ovarian Cancer. C. Halbur^, N. Choudhury, M. Chen^, J.H. Kim^, E.J. Chung, SLAS Technology, 24(2): 137-150. Featured in the USC Students Nanomedicine special issue. [link]

37. Pancreatic Gene Therapy Delivery by Nanoparticles. T. Kurtanich^, N. Roos, G. Wang^, J. Yang^, A. Wang^, E.J. Chung, SLAS Technology, 24(2): 151-160. Featured in the USC Students Nanomedicine special issue. [link]

36. Calcium-Binding Nanoparticles for Vascular Disease. D. Chin*, S. Chowdhuri^, E.J. Chung, Regenerative Engineering and Translational Medicine, 5(1): 74-85. [link]

2018

35. Hybrid, Metal Oxide-Peptide Amphiphile Micelles for Molecular Magnetic Resonance Imaging of Atherosclerosis. C. Poon#, J. Gallo, J. Joo^, T. Chang^, M. Bañobre-López, E.J. Chung, Journal of Nanobiotechnology, 16(92). [link]

34. Shape Effects of Peptide Amphiphile Micelles for Targeting Monocytes. J. Joo^, C. Poon#, S.P. Yoo, E.J. Chung, Molecules, 23(11):2786. [link]

33. First Do No Harm: Kidney Drug Targeting to Avoid Toxicity in ADPKD. E.J. Chung and K.R. Hallows, American Journal of Physiology-Renal Physiology, 3(15): F535-F536. [link]

32. Design and In Vivo Characterization of Kidney-Targeting Multimodal Micelles Toward Renal Drug Delivery. J. Wang*, C. Poon#, D. Chin*, S. Milkowski^, V. Lu^^, K.R. Hallows, E.J. Chung, Nano Research, 11(10): 5584-5595. Featured in the Young Innovator in Nanobiotechnology issue and selected for the back cover. [link]

31. Theranostic Nanoparticles for Tracking and Monitoring Disease State. C. Zavaleta, D. Ho, E. J. Chung, SLAS Technology. 23(3): 281-293. [link] Featured here. 

30. Engineering Citric-Acid Based Porous Scaffolds for Bone Regeneration, J. J. Masehi-Lano+ and E. J. Chung, Methods in Molecular Biology, Biomaterials for Tissue Engineering: Methods and Protocol: 1-10 (book chapter). [link]

2017

29. Protein Mimetic and Anticancer Properties of Monocyte-Targeting Peptide Amphiphile Micelles. C. Poon#, S. Chowdhuri^, C-H. Kuo, Y. Fang, F. Alenghat, D. Hyatt, K. Kani, M. Gross, E. J. Chung, ACS Biomaterials Science and Engineering, 3(12): 3273-3282. [link]

28. Synthesis of Monocyte-Targeting Peptide Amphiphile Micelles for Atherosclerosis, C. Poon#, M. Sarkar^, E. J. Chung, JoVE, 129 [link].

27. Peptide and Antibody Ligands for Renal Targeting: Nanomedicine Strategies for Kidney Disease. J. Wang*, J. J. Masehi-Lano+, and E. J. Chung, Biomaterials Science, 5(8): 1450-1459. [link] Featured in the Emerging Investigators issue. 

26. Targeting Cell Adhesion Molecules with Nanoparticles Using In Vivo and Flow-Based In Vitro Models of Atherosclerosis, K. Khodabandehlou#, J. J. Masehi-Lano+, C. Poon#, J. Wang*, E. J. Chung, Experimental Biology and Medicine, 242(8): 799-812. [link]

25. Bulk and Nanoscale Polypeptide Based Polyelectrolyte Complexes, A. B. Marciel, E. J. Chung, B.K. Brettmann, L. Leon, Advances in Colloid and Interface Science, 239: 187-198. [link]

24. A Biodegradable Tri-component Graft for Anterior Cruciate Ligament Reconstruction, E. J. Chung, M. J. Sugimoto, J. L. Koh, G. A. Ameer, Journal of Tissue Engineering and Regenerative Medicine, 11(3): 704-712. [link] Featured on the front cover.

2016

23. Targeting and Therapeutic Peptides in Nanomedicine for Atherosclerosis, E. J. Chung, Experimental Biology and Medicine, 241(9):891-898. [link]

22. Gadolinium-Functionalized Peptide Amphiphile Micelles for Multimodal Imaging of Atherosclerotic Lesions, S. P. Yoo, F. Pineda, J. C. Barrett, C. Poon#, M. Tirrell, E. J. Chung, ACS Omega, 1(5):996-1003. [link]

21. Self-Assembling Peptide-Based Building Blocks in Medical Applications, H. Acar, S. Srivastava, E. J. Chung, M.R. Schnorenberg, J.C. Barrett, J.L. LaBelle, M. Tirrell, Advanced Drug Delivery Reviews, 110-111: 65-79. [link]

20. Peptide Amphiphile Micelles from Structure to Function. In: Handbook of Lipid Membranes, E. J. Chung, L. Leon, K. Hunt, M. Tirrell (In press, book chapter).

2015

19. Recent Advances in Targeted, Self-Assembling Nanoparticles to Address Vascular Damage Due to Atherosclerosis, E. J. Chung, M. Tirrell, Advanced Healthcare Materials, 4(16):2408-2422. [link] Featured on the front cover and Advanced Science News. 

18. Biocompatibility and Characterization of a Peptide Amphiphile Hydrogel for Applications in Peripheral Nerve Regeneration, K. A. Black, B. F. Lin, E. A. Wonder, S. S. Desai, E. J. Chung, B. Ulery, R. S. Katari, M. Tirrell, Tissue Engineering Part A, 21(7-8):1333-1342 (2015). [link]

17. In Vivo Biodistribution and Clearance of Peptide Amphiphile Micelles, E. J. Chung, L. B. Mlinar, M. J. Sugimoto, K. Nord, B. B. Roman, M. Tirrell, Nanomedicine: Nanotechnology, Biology and Medicine, 11 (2): 479-487 (2015). [link]

16. Monocyte-Targeting Supramolecular Micellar Assemblies: A Molecular Diagnostic Tool for Atherosclerosis, E. J. Chung, L. B. Mlinar, K. Nord, M. J. Sugimoto, E. Wonder, F. J. Alenghat, Y. Fang, M. Tirrell, Adv. Healthcare Mater., 4(3):367-376 (2015). [link] Featured on the inside front cover.

2014

15. Fibrin-Targeting, Peptide Amphiphile Micelles as Contrast Agents for Molecular MRI, E. J. Chung, F. Pineda, K. Nord, G Karczmar, S.-K. Lee, M. Tirrell, J. Cell Sci. Ther., 5, 181 (2014). [link]

14. Inhibition of Atherosclerosis-Promoting microRNAs via Targeted Polyelectrolyte Complex Micelles, C-H. Kuo, L. Leon, E. J. Chung, T. Sontag, R-T. Huang, C. Reardon, G. Getz, M. Tirrell, Y. Fang, J. Mater. Chem. B, 2, 8142-8153 (2014). [link] Featured on the back cover.

13. Active Targeting of Early and Mid-Stage Atherosclerotic Plaques using Self-Assembled Peptide Amphiphile Micelles, L. Mlinar, E.J. Chung, E. Wonder, M. Tirrell, Biomaterials,35(30), 8678–8686 (2014). [link]

12. Fibrin-Binding, Peptide Amphiphile Micelles for Targeting Glioblastoma, E.J. Chung, Y. Cheng, R. Morshed, K. Nord, Y. Han, M. Wegscheid, B. Auffinger, D.A. Wainwright, M.S. Lesniak, M.V. Tirrell, Biomaterials, 35, 1249-1256 (2014). [link]

11. Investigation of Soy Protein Hydrogels for Biomedical Applications: Materials Characterization, Drug Release, and Biocompatibility, K.B. Chien, E.J. Chung, and R.N. Shah, Journal of Biomaterials Applications, 28(7), 1085-1096 (2014). [link]

2013

10. Chapter 13: Nanomaterials for Cartilage Regeneration in Nanomaterials in Tissue Engineering: Characterization, Fabrication and Applications. E.J. Chung, N. Shah, and R.N. Shah (2013, book chapter).

9. Osteogenic Potential of BMP‐2‐Releasing Self‐Assembled Membranes, E.J. Chung, K.B. Chien, B.A. Aguado, and R.N. Shah, Tissue Engineering Part A, 19(23-24), 2664-2673 (2013). [link]

8. In Situ Forming Collagen‐Hyaluronic Acid Membrane Structures: Mechanism of Self‐Assembly and Applications in Regenerative Medicine, E.J. Chung, A.E. Jakus, and R.N. Shah, Acta Biomaterialia, 9(2), 5153‐5161 (2013). [link]

2012

7. Low Pressure Foaming: A Novel Method for the Fabrication of Porous Scaffolds for Tissue Engineering, E.J. Chung, M. Sugimoto, J. Koh, and G.A. Ameer, Tissue Engineering Part C, 18(2) 113‐121 (2012). [link] Featured on the front cover. 

2011

6. The Role of Hydroxyapatite in Citric Acid‐Based Nanocomposites: Surface Characteristic, Degradation, and Osteogenicity, E.J. Chung, M. Sugimoto, and G.A. Ameer, Acta Biomaterilia, 7(11), 4057‐4063 (2011). [link]

5. Long‐Term In Vivo Response to Citric Acid‐Based Nanocomposites for Orthopaedic Tissue Engineering, E.J. Chung, P. Kodali, S. Yang, W. Laskin, J. Koh, and G.A. Ameer, Journal of Materials Science: Materials in Medicine, 22(9), 2131‐2138 (2011). [link]

4. Early Tissue Response to Citric Acid‐Based Micro‐ and Nanocomposites, E.J. Chung, H.J. Qiu, P. Kodali, S. Yang, J. Hwong, J.Koh, and G.A. Ameer, Journal of Biomedical Materials Research Part A, 96A(1): 29‐37 (2011). [link]

2010

3. Allopregnanolone Reverses Neurogenic and Cognitive Deficits in Mouse Model of Alzheimer’s Disease, J. Wang, C. Singh, L. Liu, R. Irwin, S. Chen, E.J. Chung, R. Thompson, and R. Brinton, PNAS, 107(14) 6498‐6503 (2010). [link]

2. Advances and Applications of Biodegradable Elastomers in Regenerative Medicine, M.C. Serrano, E.J. Chung, and G.A. Ameer, Advanced Functional Materials, 20(2) 192‐208 (2010). [link]

2006

1. Focal Adhesion and Actin Organization by a Cross‐Talk of TM4SF5 with Integrin a2 are Regulated by Serum Treatment, S.Y. Lee, T.Y. Kim, M.S. Lee, Y.B. Kim, E.J. Chung, and J.W. Lee, Experimental Cell Research, 312(16) 2983‐2999 (2006). [link]